Adipotide FTPP (10mg)

Adipotide FTPP is a proapoptotic peptide designed to target and eliminate white adipose tissue by binding to the ANXA2-prohibitin receptor complex on endothelial cells of blood vessels that support white fat. This binding disrupts fatty acid transport and induces apoptosis in these endothelial cells, cutting off the blood supply to the associated fat cells. With a molecular weight of 2611.41 g/mol and the sequence Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys—Gly-Gly–(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2, it has been shown in monkey studies to induce significant weight loss, improve insulin sensitivity, and reduce body mass index. The targeting of prohibitin, a protein also found in some cancer cells, opens additional research avenues in oncology for anti-angiogenic tumor starvation strategies.