Gonadorelin (GnRH) (10mg)

Gonadorelin is a synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH) that acts as a potent GnRH receptor agonist, stimulating synthesis and pulsatile release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. With a molecular weight of 1182.311 g/mol, its method of exposure determines function: intermittent pulsatile administration upregulates the HPG axis for studying infertility and hypogonadism, while continuous exposure downregulates receptors for oncology research in hormone-sensitive cancers by lowering gonadal steroid production. It also serves as a diagnostic tool to assess pituitary function and is studied in dementia for its anti-hormonal effects on Alzheimer’s pathology.