GHK-Cu is a naturally occurring tripeptide-copper complex found in human plasma that functions as a powerful signaling molecule modulating gene expression, released from broken-down collagen at injury sites as a ‘repair signal’ recruiting fibroblasts and immune cells while promoting angiogenesis and tissue remodeling. With a molecular weight of 340.38 g/mol, it dramatically accelerates wound healing and reduces infection rates in diabetic ulcer models by stimulating collagen, elastin, and glycosaminoglycan synthesis while reducing inflammation. It improves skin thickness and elasticity, protects against photodamage by neutralizing free radicals, stimulates nerve growth factor expression, increases proliferative potential of epidermal stem cells, and reverses metastasis-related gene expression in colon cancer cells.



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