Receptor Grade IGF-1 LR3 (100mcg) is a highly pure, potent analog of human IGF-1 with two key modifications: a 13-amino-acid N-terminal extension and an arginine substitution at position 3, which dramatically reduce its affinity for IGF Binding Proteins (IGFBPs). With a molecular weight of 9117.5 g/mol, this ‘Receptor Grade’ designation ensures the highest purity for consistent results in cell-based assays and animal studies where biological potency is critical. Its enhanced biological activity, roughly 2.5 times more potent than regular IGF-1, leads to more pronounced intracellular signaling promoting cellular proliferation, differentiation, and apoptosis inhibition, making it a critical tool for investigating the IGF signaling pathway and muscle cell biology.

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