Ipamorelin (5mg)

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2Nal-D-Phe-Lys-NH2) and highly selective agonist for the growth hormone secretagogue receptor 1a (GHS-R1a), noted for its remarkable specificity in potently stimulating GH release from pituitary somatotroph cells without significantly affecting other hormones like prolactin, ACTH, or cortisol. With a molecular weight of 711.86 g/mol, it can elevate GH levels over 60-fold from baseline, making it an ideal model for studying isolated GH release effects. Its GH/IGF-1 axis activation has been studied for preventing bone loss, increasing bone mineral density, countering muscle wasting, promoting insulin release from pancreatic islet cells, and accelerating gastric emptying in post-operative ileus models.