PT-141 is a synthetic peptide analog of Melanotan II that acts as a potent and selective agonist for the Melanocortin-4 Receptor (MC4R) in the central nervous system, with a molecular weight of 1025.18 g/mol. Its effects on sexual function are mediated through MC4R activation, influencing neural pathways involved in sexual processing by enhancing activity in motor control regions while reducing sensory processing area activation. This dual action enhances both physiological and psychological aspects of sexual arousal for up to 24 hours, potentially through enhancing nitric oxide release in cavernosal tissues to promote vasodilation, and its interaction with MC1R suggests research applications in cell survival and DNA repair pathways.


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