FOXO4-DRI (Proxofim) (10mg)

FOXO4-DRI is a synthetic D-Retro-Inverso peptide designed to selectively target and eliminate senescent cells by disrupting the binding between endogenous FOXO4 and p53, restoring p53’s ability to initiate apoptosis in these harmful ‘zombie cells’. With exceptional stability from its D-amino acid composition, it effectively clears senescent cells to reduce chronic inflammation and restore tissue function, improving healthspan in aged models. It shows promise in diabetes models by regulating insulin signaling, in cardiovascular research by promoting autophagy and clearing damaged proteins, and in neurodegenerative diseases by reducing inflammation and restoring a healthier cellular environment.