GHK Basic (Glycyl-L-histidyl-L-lysine) is the non-copper-bound form of the copper peptide GHK-Cu, a naturally occurring signaling molecule released from breakdown of collagen and SPARC at injury sites that acts as a powerful chemoattractant and gene regulator. With a molecular weight of 340.4 g/mol, it profoundly influences gene expression by upregulating hundreds of genes involved in tissue repair, antioxidant defense, and DNA repair while downregulating pro-inflammatory genes. It accelerates wound closure and reduces infection rates, neutralizes harmful free radicals, reduces pro-oxidant iron release, reverses metastasis-prone gene expression in colorectal cancer cells, suppresses fibrinogen beta chain to inhibit thrombus formation, and stimulates TGF-beta production for initiating repair processes.



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