GHRP-6 is a synthetic hexapeptide (His-D-Trp-Ala-Trp-D-Phe-Lys) and well-characterized growth hormone secretagogue that acts as a potent agonist for the ghrelin receptor (GHS-R1a) on pituitary somatotrophs and hypothalamic neurons, triggering calcium mobilization and potent GH release. With a molecular weight of 873.03 g/mol, it has demonstrated neuroprotective properties in stroke and Parkinson’s disease models by protecting neurons from apoptosis and reducing inflammation via Akt pathway activation. It also promotes cell survival and repair by potentially binding to CD36 receptors to reduce fibrosis and improve wound healing, and influences the central nervous system to modulate sexual behavior and exhibit antidepressant-like effects in animal models.


Reviews
There are no reviews yet.