SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide for in-vitro studies of cardiolipin interactions, bioenergetics, and redox balance.
SS-31 (Elamipretide)
This aromatic–cationic tetrapeptide associates with inner-mitochondrial-membrane lipids (notably cardiolipin). Consequently, researchers employ it to explore electron-transport organisation, bioenergetics, and redox pathways in model systems.
For laboratory research only. Not for human use.
SS-31 Key features
- Mitochondria-targeted tetrapeptide for bioenergetics and redox studies in vitro.
- Supplied as a lyophilised solid for stability and straightforward storage.
- Unit size: 10 mg per vial.
- Each batch released only after stringent quality checks.
Specifications

- Product name: SS-31
- Synonyms: Elamipretide; MTP-131; Bendavia; Szeto–Schiller peptide
- Sequence (one-letter): D-Arg–Dmt–Lys–Phe–NH2 (Dmt = 2′,6′-dimethyltyrosine)
- Form: Lyophilised powder
- Unit size: 10 mg
- Appearance: White to off-white solid
- Note: Exact properties may vary by counterion/hydration state (e.g., acetate/TFA).
Handling & storage
- Storage (dry): Keep vials protected from light and moisture.
- Reconstitution: Bring vial and diluent to room temperature. Reconstitute with
Bacteriostatic Water 10 ml. Swirl gently—do not vortex. - After reconstitution: Store at 2–8 °C, protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling.
- Compatibility: Use only within research protocols that follow your lab’s SOPs and local regulations.
Looking for complementary materials? See
Bacteriostatic Water 10 ml and mitochondrial research peptides such as
MOTS-c 10 mg.
About SS-31 in research
The alternating aromatic–cationic motif supports membrane association in model systems. Researchers use SS-31 to examine interactions with cardiolipin-rich domains, assess effects on respiratory-chain organisation, and probe consequences for mitochondrial reactive-species handling and ATP-linked metabolism—exclusively in controlled, non-clinical in-vitro contexts.
Synthesis & quality
Manufactured via controlled, validated peptide-synthesis processes to deliver high purity and lot-to-lot consistency. Each batch undergoes identity, purity, and appearance checks before release.
Legal & safety
XL Peptides supplies materials strictly for laboratory research. Products are not medications, foods, supplements, or cosmetics; not for human or veterinary use. By purchasing, you confirm you are a qualified researcher and will handle the material in line with your institution’s policies and applicable laws.
FAQs
What is SS-31?
An aromatic–cationic tetrapeptide (D-Arg–Dmt–Lys–Phe–NH2) used to study mitochondrial membranes, cardiolipin interactions, and bioenergetics in vitro.
How should I store the peptide?
Keep lyophilised vials away from light and moisture. After reconstitution, store at 2–8 °C, protect from light, and avoid repeated temperature cycling.










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